CUSTOM ITEM: HPLC Column, Diamond Hydride, 4 um, 3.0 mm ID x 50 mm Length, 100 A. Cogent TYPE-C Brand. 1 EA.
Additional Info:
The 70000‑05P‑3 Diamond Hydride HPLC Column is a compact, solvent‑saving analytical column designed for fast and efficient separations of polar and mixed‑polarity compounds. Built on proven Cogent TYPE‑C™ silica hydride technology, this column delivers excellent retention, rapid equilibration, and robust reproducibility using conventional HPLC and LC‑MS instrumentation.
The 3.0 mm × 50 mm format is especially well suited for high‑throughput screening, method development, and routine analyses where reduced run times and lower solvent consumption are priorities.
Why This Column Is Used
The 3.0 mm internal diameter provides a practical balance between traditional analytical columns and microbore formats, offering:
Reduced mobile‑phase consumption compared to 4.6 mm ID columns
Shorter run times with efficient separations
Compatibility with standard HPLC and LC‑MS systems
Straightforward method scaling from conventional analytical formats
This column is frequently selected when laboratories want improved efficiency and cost control without transitioning to low‑flow or specialized instrumentation.
Diamond Hydride™ Stationary Phase Advantage
Manufactured using Cogent TYPE‑C™ silica hydride technology, the Diamond Hydride stationary phase offers fundamental advantages over traditional bonded‑silica HILIC columns:
Faster equilibration, minimizing downtime between injections
Stable and reproducible retention, even at high organic solvent levels
Extended column lifetime for routine analytical use
The silica hydride surface supports mixed‑mode retention mechanisms, making it particularly effective for analytes that are difficult to retain or resolve using conventional reversed‑phase or amide‑based HILIC columns.
Typical Applications
This column is routinely used for the analysis of:
Small, highly polar molecules
Amino acids and organic acids
Polar and mixed‑polarity peptides
Metabolites and other biologically relevant compounds
It is well suited for both development and routine analytical workflows.
Fast, Efficient HPLC and LC‑MS Analysis
The 50 mm column length enables short analysis times while maintaining adequate resolution for many screening and routine methods. This makes the 70000‑05P‑3 especially effective for:
High‑throughput analytical workflows
Rapid method scouting and optimization
LC‑MS applications where speed and solvent reduction are critical
The reduced column volume helps improve system efficiency without introducing the complexity associated with narrow‑bore columns.
System Requirements
Typical operating flow rates: ~0.4–0.6 mL/min, depending on method and solvent composition
Compatible with standard analytical HPLC and LC‑MS systems
No specialized low‑flow hardware required
Flow rates and conditions may be optimized based on resolution requirements, pressure limits, and detector configuration.